Cell-type and subcellular compartment-specific APEX2 proximity labeling reveals activity-dependent nuclear proteome dynamics in the striatum

Keyphrases

• Activity-dependent 100%
• Compartment-specific 100%
• Development Organizations 25%
• Direct Pathway 25%
• Electron Mass 25%
• Electron Microscopy 25%
• Flexible Manufacturing Cell 25%
• Functional Organization 25%
• Incomplete Capture 25%
• Indirect Pathway 25%
• Information Capture 25%
• Isolation Method 25%
• Labeling Approach 25%
• Mass Spectrometry 25%
• Mouse Brain 50%
• Multiple Tissues 25%
• Neural Circuits 25%
• Neuronal Subtypes 25%
• Neuroproteome 25%
• Nuclear Proteome 100%
• Protein Isolation 25%
• Proteome 75%
• Proteome Dynamics 100%
• Proximity Labeling 100%
• Quantitative Profiling 25%
• Signaling Cascades 25%
• Specific Information 25%
• Spiny Projection Neurons 25%
• Striatal Neurons 25%
• Striatum 100%
• Subcellular Compartments 100%
• Subcellular Proteomics 50%
• Transcriptome 25%
• Type-specific 100%
• Vertebrate Brain 25%

Biochemistry, Genetics and Molecular Biology

• Dynamics 100%
• Electron Microscopy 16%
• Mass Spectrometry 16%
• Protein Isolation 16%
• Proteome 100%
• Transcriptome 16%