Cellular immune responses against viral pathogens in shrimp

Dandan Xu, Weifeng Liu, Angel Alvarez, Tianzhi Huang*

*Corresponding author for this work

Research output: Contribution to journalReview article

29 Scopus citations

Abstract

Shrimp is one of the most important commercial marine species worldwide; however, viral diseases threaten the healthy development of shrimp aquaculture. In order to develop efficient control strategies against viral diseases, researchers have begun focusing increasing attention to the molecular mechanism of shrimp innate immunity. Although knowledge of shrimp humoral immunity has grown significantly in recent years, very little information is available about the cell-mediated immune responses. Several cellular processes such as phagocytosis, apoptosis, and RNA interference critical in cellular immune response play a significant role in endogenous antiviral activity in shrimp. In this review, we summarize the emerging research and highlight key mediators of cellular immune response to viral pathogens.

Original languageEnglish (US)
Pages (from-to)287-297
Number of pages11
JournalDevelopmental and Comparative Immunology
Volume47
Issue number2
DOIs
StatePublished - Dec 1 2014

Keywords

  • Apoptosis
  • Phagocytosis
  • RNAi
  • Shrimp

ASJC Scopus subject areas

  • Immunology
  • Developmental Biology

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