Central Airways Obstruction Due to Aspergillus fumigatus After Lung Transplantation

Elizabeth Cerceo; Robert M. Kotloff; Denis Hadjiliadis; Vivek N. Ahya; Alberto Pochettino; Colin Gillespie; Jason D. Christie

doi:10.1016/j.healun.2009.01.024

Central Airways Obstruction Due to Aspergillus fumigatus After Lung Transplantation

Elizabeth Cerceo, Robert M. Kotloff, Denis Hadjiliadis, Vivek N. Ahya, Alberto Pochettino, Colin Gillespie, Jason D. Christie^*

^*Corresponding author for this work

Medicine, Pulmonary Division

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Aspergillus fumigatus may affect immunocompromised lung transplant patients in many ways. We report a new pulmonary manifestation of A fumigatus in 3 patients who underwent bilateral lung transplantation. All 3 subjects developed rapid decreases in pulmonary function and were found to have large central airways obstruction with thick plugs of mucus, heavily laden with Aspergillus species. All 3 patients presented with atypical features of Aspergillus infection, but all responded to treatments with either steroids, anti-fungals or both.

Original language	English (US)
Pages (from-to)	515-519
Number of pages	5
Journal	Journal of Heart and Lung Transplantation
Volume	28
Issue number	5
DOIs	https://doi.org/10.1016/j.healun.2009.01.024
State	Published - May 2009

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Transplantation
Pulmonary and Respiratory Medicine
Surgery

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abstract = "Aspergillus fumigatus may affect immunocompromised lung transplant patients in many ways. We report a new pulmonary manifestation of A fumigatus in 3 patients who underwent bilateral lung transplantation. All 3 subjects developed rapid decreases in pulmonary function and were found to have large central airways obstruction with thick plugs of mucus, heavily laden with Aspergillus species. All 3 patients presented with atypical features of Aspergillus infection, but all responded to treatments with either steroids, anti-fungals or both.",

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AU - Pochettino, Alberto

AU - Gillespie, Colin

AU - Christie, Jason D.

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AB - Aspergillus fumigatus may affect immunocompromised lung transplant patients in many ways. We report a new pulmonary manifestation of A fumigatus in 3 patients who underwent bilateral lung transplantation. All 3 subjects developed rapid decreases in pulmonary function and were found to have large central airways obstruction with thick plugs of mucus, heavily laden with Aspergillus species. All 3 patients presented with atypical features of Aspergillus infection, but all responded to treatments with either steroids, anti-fungals or both.

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Central Airways Obstruction Due to Aspergillus fumigatus After Lung Transplantation

Abstract

ASJC Scopus subject areas

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