Central nervous system relapse of treated stage IV neuroblastoma

Susan Palasis*, John C. Egelhoff, Joan D. Morris, Bernadette L. Koch, William S. Ball

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Neuroblastoma is the most common extracranial solid tumor in pediatrics. The long-term survival of patients with advanced stage neurobastoma has remarkably improved secondary to aggressive treatment protocols including autologous bone marrow transplant (BMT). As a result, a different natural history of this disease is being reported with unusual, late manifestations. The central nervous system (CNS), once a rare site of disease, is being involved with increasing frequency. Appropriate neuroimaging in these patients is important. Two cases of patients with treated stage IV neuroblastoma who developed isolated CNS metastases are presented. The proposed pathogenesis and neuroradiologic manifestations of this complication are reviewed.

Original languageEnglish (US)
Pages (from-to)990-994
Number of pages5
JournalPediatric radiology
Issue number12
StatePublished - Dec 1 1998

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Radiology Nuclear Medicine and imaging


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