Central nervous system Sjögren's syndrome in a child: Case report and review of the literature

Jay A. Gottfried, Terri H. Finkel, Jill V. Hunter, David F. Carpentieri, Richard S. Finkel

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

We describe a case of pediatric Sjögren's syndrome with progressive neurologic involvement. At age 4 years, she had been diagnosed with Melkersson-Rosenthal syndrome. After being stable with facial diplegia and swelling for 5 years, she acutely presented with diplopia, vertigo, and ataxia. Cranial magnetic resonance imaging (MRI) showed a left dorsal midbrain lesion. Serologic and histopathologic findings confirmed primary Sjögren's syndrome. She responded well to intravenous methylprednisolone, with subsequent clinical improvement and MRI resolution. This report reviews the pediatric literature and underscores the importance of considering Sjögren's syndrome in a child with unexplained facial weakness and in the differential diagnosis of pediatric stroke.

Original languageEnglish (US)
Pages (from-to)683-685
Number of pages3
JournalJournal of Child Neurology
Volume16
Issue number9
DOIs
StatePublished - Jan 1 2001

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Central nervous system Sjögren's syndrome in a child: Case report and review of the literature'. Together they form a unique fingerprint.

Cite this