Abstract
Collins et al. describe the role of centriole number and microtubules during the developmental process of radial intercalation in the skin of Xenopus embryos. Increasing the number of centrioles and/or microtubules within an intercalating cell drives early apical insertion, whereas decreasing centrioles and microtubules delays insertion.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1958-1964.e3 |
| Journal | Current Biology |
| Volume | 30 |
| Issue number | 10 |
| DOIs | |
| State | Published - May 18 2020 |
Funding
This work was supported by NIH/NIGMS ( R01GM119322 ). We would like to thank Jen Mitchell for helpful comments during preparation of this manuscript. We would like to thank the National Xenopus Resource and the Marine Biological Laboratories for technical support and reagents. This work was supported by NIH/NIGMS (R01GM119322). We would like to thank Jen Mitchell for helpful comments during preparation of this manuscript. We would like to thank the National Xenopus Resource and the Marine Biological Laboratories for technical support and reagents. C.C. and B.M. conceived and designed experiments. C.C. and A.M. performed experiments and analyzed the data. C.C. and B.M. prepared the figures and wrote the manuscript. The authors declare no competing interests.
Keywords
- , microtubule
- Xenopus
- apical insertion
- centriole
- ionocyte
- migration
- mulitciliated cell
- radial intercalation
ASJC Scopus subject areas
- General Neuroscience
- General Biochemistry, Genetics and Molecular Biology
- General Agricultural and Biological Sciences