Abstract
The Mis18 complex is a critical player in determining when and where centromeres are built. A new study identifies Polo-like kinase (Plk1) as a positive regulator required for the localization of Mis18 to centromeres. This is a critical step that is essential for proper centromere function and maintaining the integrity of the genome.
Original language | English (US) |
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Pages (from-to) | R808-R810 |
Journal | Current Biology |
Volume | 24 |
Issue number | 17 |
DOIs | |
State | Published - Sep 8 2014 |
ASJC Scopus subject areas
- General Biochemistry, Genetics and Molecular Biology
- General Agricultural and Biological Sciences