Cerebral and tissue oximetry

Jochen Steppan, Charles W. Hogue*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

105 Scopus citations

Abstract

The use of near-infrared spectroscopy (NIRS) has been increasingly adopted in cardiac surgery to measure regional cerebral oxygen saturation. This method takes advantage of the fact that light in the near-infrared spectrum penetrates tissue, including bone and muscle. Sensors are placed at fixed distances from a light emitter, and algorithms subtract superficial light absorption from deep absorption to provide an index of tissue oxygenation. Although the popularity of NIRS monitoring is growing, definitive data that prove outcome benefits with its use remain sparse. Therefore, widespread, routine use of NIRS as a standard-of-care monitor cannot be recommended at present. Recent investigations have focused on the use of NIRS in subgroups that may benefit from NIRS monitoring, such as pediatric patients. Furthermore, a novel application of processed NIRS information for monitoring cerebral autoregulation and tissue oxygenation (e.g., kidneys and the gut) is promising.

Original languageEnglish (US)
Pages (from-to)429-439
Number of pages11
JournalBest Practice and Research: Clinical Anaesthesiology
Volume28
Issue number4
DOIs
StatePublished - 2014

Funding

Supported in part by a grant to Dr. Hogue from the National Institutes of Health ( R01 HL092259-1 ). Charles W Hogue, Jr.: Research funding from Covidien, Inc (Boulder, CO), Advisory Board Membership for Ornim (Israel), Data and Safety Montioring Board , CSL Behring (King of Prussia, PA). The IRB number is NA00077079 and the clinicalTrials.gov identifier is NCT01765504.

Keywords

  • Anesthesia
  • Cardiac surgery
  • Cerebral autoregulation
  • Monitor
  • NIRS
  • Near-infrared spectroscopy

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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