Cerebral embolism associated with left ventricular assist device support and successful therapy with intraarterial urokinase

Vigneshwar Kasirajan; Nicholas G. Smedira; John Per; Patrick M. McCarthy

doi:10.1016/S0003-4975(99)00091-0

Cerebral embolism associated with left ventricular assist device support and successful therapy with intraarterial urokinase

Vigneshwar Kasirajan, Nicholas G. Smedira^*, John Per, Patrick M. McCarthy

^*Corresponding author for this work

Surgery, Cardiac Surgery Division

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A patient with a bioprosthetic aortic valve sustained a cerebral embolism during support with an implantable left ventricular assist device. This was lysed with intraarterial urokinase with complete resolution of the neurological deficit. Subsequently the patient underwent heart transplantation and remains neurologically intact. This case report is the first successful use of thrombolysis for cerebral embolism associated with a mechanical assist device.

Original language	English (US)
Pages (from-to)	1148-1150
Number of pages	3
Journal	Annals of Thoracic Surgery
Volume	67
Issue number	4
DOIs	https://doi.org/10.1016/S0003-4975(99)00091-0
State	Published - Apr 1 1999

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Surgery

Access to Document

10.1016/S0003-4975(99)00091-0

Fingerprint Dive into the research topics of 'Cerebral embolism associated with left ventricular assist device support and successful therapy with intraarterial urokinase'. Together they form a unique fingerprint.

Cite this

@article{658007a6c76e4306a15241eacd779f45,

title = "Cerebral embolism associated with left ventricular assist device support and successful therapy with intraarterial urokinase",

abstract = "A patient with a bioprosthetic aortic valve sustained a cerebral embolism during support with an implantable left ventricular assist device. This was lysed with intraarterial urokinase with complete resolution of the neurological deficit. Subsequently the patient underwent heart transplantation and remains neurologically intact. This case report is the first successful use of thrombolysis for cerebral embolism associated with a mechanical assist device.",

author = "Vigneshwar Kasirajan and Smedira, {Nicholas G.} and John Per and McCarthy, {Patrick M.}",

year = "1999",

month = apr,

day = "1",

doi = "10.1016/S0003-4975(99)00091-0",

language = "English (US)",

volume = "67",

pages = "1148--1150",

journal = "Annals of Thoracic Surgery",

issn = "0003-4975",

publisher = "Elsevier USA",

number = "4",

}

TY - JOUR

T1 - Cerebral embolism associated with left ventricular assist device support and successful therapy with intraarterial urokinase

AU - Kasirajan, Vigneshwar

AU - Smedira, Nicholas G.

AU - Per, John

AU - McCarthy, Patrick M.

PY - 1999/4/1

Y1 - 1999/4/1

N2 - A patient with a bioprosthetic aortic valve sustained a cerebral embolism during support with an implantable left ventricular assist device. This was lysed with intraarterial urokinase with complete resolution of the neurological deficit. Subsequently the patient underwent heart transplantation and remains neurologically intact. This case report is the first successful use of thrombolysis for cerebral embolism associated with a mechanical assist device.

AB - A patient with a bioprosthetic aortic valve sustained a cerebral embolism during support with an implantable left ventricular assist device. This was lysed with intraarterial urokinase with complete resolution of the neurological deficit. Subsequently the patient underwent heart transplantation and remains neurologically intact. This case report is the first successful use of thrombolysis for cerebral embolism associated with a mechanical assist device.

UR - http://www.scopus.com/inward/record.url?scp=0032943491&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032943491&partnerID=8YFLogxK

U2 - 10.1016/S0003-4975(99)00091-0

DO - 10.1016/S0003-4975(99)00091-0

M3 - Article

C2 - 10320266

AN - SCOPUS:0032943491

VL - 67

SP - 1148

EP - 1150

JO - Annals of Thoracic Surgery

JF - Annals of Thoracic Surgery

SN - 0003-4975

IS - 4

ER -