Abstract
The hy-3/hy-3 mouse is a model of congenital hydrocephalus. The development of the subarachnoid space and extracellular space were studied in normal and hydrocephalic animals. A previous space in the mesenchyme is altered to form the subarachnoid space. Changes in the extracellular space demonstrate that this space is dynamic and acts to compensate for events occurring in the ventricular system. The aqueduct and central spinal canal are also involved in the hydrocephalic process. Change in cerebral vasculature may indicate the processes which lead to irreversibility.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 293-303 |
| Number of pages | 11 |
| Journal | Child's Brain |
| Volume | 5 |
| Issue number | 3 |
| State | Published - Jan 1 1979 |
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ASJC Scopus subject areas
- Clinical Neurology
- Pediatrics, Perinatology, and Child Health
- Neuroscience(all)
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Cerebrospinal fluid pathways in a murine mutant. / McLone, D. G.
In: Child's Brain, Vol. 5, No. 3, 01.01.1979, p. 293-303.Research output: Contribution to journal › Article
TY - JOUR
T1 - Cerebrospinal fluid pathways in a murine mutant.
AU - McLone, D. G.
PY - 1979/1/1
Y1 - 1979/1/1
N2 - The hy-3/hy-3 mouse is a model of congenital hydrocephalus. The development of the subarachnoid space and extracellular space were studied in normal and hydrocephalic animals. A previous space in the mesenchyme is altered to form the subarachnoid space. Changes in the extracellular space demonstrate that this space is dynamic and acts to compensate for events occurring in the ventricular system. The aqueduct and central spinal canal are also involved in the hydrocephalic process. Change in cerebral vasculature may indicate the processes which lead to irreversibility.
AB - The hy-3/hy-3 mouse is a model of congenital hydrocephalus. The development of the subarachnoid space and extracellular space were studied in normal and hydrocephalic animals. A previous space in the mesenchyme is altered to form the subarachnoid space. Changes in the extracellular space demonstrate that this space is dynamic and acts to compensate for events occurring in the ventricular system. The aqueduct and central spinal canal are also involved in the hydrocephalic process. Change in cerebral vasculature may indicate the processes which lead to irreversibility.
UR - http://www.scopus.com/inward/record.url?scp=0018370621&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018370621&partnerID=8YFLogxK
M3 - Article
VL - 5
SP - 293
EP - 303
JO - Child's Brain
JF - Child's Brain
SN - 0302-2803
IS - 3
ER -