Cerebrospinal fluid pathways in a murine mutant.

D. G. McLone

Cerebrospinal fluid pathways in a murine mutant.

D. G. McLone^*

^*Corresponding author for this work

Neurological Surgery

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

The hy-3/hy-3 mouse is a model of congenital hydrocephalus. The development of the subarachnoid space and extracellular space were studied in normal and hydrocephalic animals. A previous space in the mesenchyme is altered to form the subarachnoid space. Changes in the extracellular space demonstrate that this space is dynamic and acts to compensate for events occurring in the ventricular system. The aqueduct and central spinal canal are also involved in the hydrocephalic process. Change in cerebral vasculature may indicate the processes which lead to irreversibility.

Original language	English (US)
Pages (from-to)	293-303
Number of pages	11
Journal	Child's Brain
Volume	5
Issue number	3
State	Published - Jan 1 1979

ASJC Scopus subject areas

Clinical Neurology
Pediatrics, Perinatology, and Child Health
Neuroscience(all)

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