Cerebrovascular Disease

Philip B. Gorelick, Jiangyong Min, Muhammad Umar Farooq

Research output: Chapter in Book/Report/Conference proceedingChapter


Stroke is the second leading cause of mortality worldwide. Proper management of hypertension plays a major role in the prevention and treatment of stroke. It is estimated that between 25% and 50% of strokes may be attributed to hypertension. Advances in neuroimaging have led to a new definition of stroke that has replaced the prior time-based definition to one of tissue-based findings on acute magnetic resonance imaging and cranial computed tomography. New targets for blood pressure lowering in the acute, subacute, and chronic stages of stroke are being established based on observational epidemiologic studies and randomized controlled clinical trials. Raised blood pressure has been one of the most thoroughly studied risk factors in relation to stroke. In this chapter, we discuss blood pressure in the context of stroke prevention, acute treatment, recurrent prevention, and maintenance of cognition, with an emphasis on contemporary stroke guidelines emanating from the United States.

Original languageEnglish (US)
Title of host publicationHypertension
Subtitle of host publicationA Companion to Braunwald's Heart Disease
Number of pages12
ISBN (Electronic)9780323883696
ISBN (Print)9780323931731
StatePublished - Jan 1 2023


  • acute treatment
  • blood pressure lowering medications.
  • hypertension
  • prevention
  • stroke

ASJC Scopus subject areas

  • General Medicine


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