Cerebrovascular Hemodynamics in Women

Cristina Duque, Steven K. Feske, Farzaneh A. Sorond*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Sex and gender, as biological and social factors, significantly influence health outcomes. Among the biological factors, sex differences in vascular physiology may be one specific mechanism contributing to the observed differences in clinical presentation, response to treatment, and clinical outcomes in several vascular disorders. This review focuses on the cerebrovascular bed and summarizes the existing literature on sex differences in cerebrovascular hemodynamics to highlight the knowledge deficit that exists in this domain. The available evidence is used to generate mechanistically plausible and testable hypotheses to underscore the unmet need in understanding sex-specific mechanisms as targets for more effective therapeutic and preventive strategies.

Original languageEnglish (US)
Pages (from-to)679-688
Number of pages10
JournalSeminars in Neurology
Volume37
Issue number6
DOIs
StatePublished - Dec 1 2017

Keywords

  • cerebral autoregulation
  • cerebral vasoreactivity
  • cerebrovascular hemodynamics
  • neurovascular coupling
  • women

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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