Cerebrovascular physiology in liver disease

Jeffrey DellaVolpe, Minjee Kim, Thomas P Bleck, Ali Al-Khafaji*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Mental status changes in acute and chronic liver disease can account for a significant portion of ICU admissions and mortality. Much of the pathology associated with these conditions is associated with an inability to maintain adequate blood flow. Thus, an understanding of both normal cerebrovascular physiology as well as the physiology behind derangements seen in both acute and chronic liver failure can help lead to better understanding and optimized management of these critically ill patients. Keywords

Original languageEnglish (US)
Title of host publicationHepatic Critical Care
PublisherSpringer International Publishing
Number of pages13
ISBN (Electronic)9783319664323
ISBN (Print)9783319664316
StatePublished - Jan 8 2018


  • Acute liver failure
  • Autoregulation
  • Cerebral edema
  • Cerebral perfusion pressure
  • Hepatic encephalopathy

ASJC Scopus subject areas

  • Medicine(all)


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