@inproceedings{dae5632b76cb4a68b4d8fa7cb708b57c,
title = "Challenges of detecting bioterrorism agents in complex matrices",
abstract = "This chapter offers an overview of the shift from the use of mass-spectrometry for studying purified bioterrorism agents to the development of methods for rapid detection thereof in environmental and clinical samples. We discuss the difficulties of working with such complex matrices and present methods for quickly and effectively reducing complexity through sample preparation. Finally, we examine a success story wherein the common pathogen and potential bioterrorism agent norovirus is detected at clinically relevant levels in human stool.",
keywords = "Environmental samples, clinical samples, norovirus, stool",
author = "Hartmann, {Erica M.} and Halden, {Rolf U.}",
note = "Copyright: Copyright 2021 Elsevier B.V., All rights reserved.",
year = "2011",
doi = "10.1007/978-90-481-9815-3_10",
language = "English (US)",
isbn = "9789048198146",
series = "NATO Science for Peace and Security Series A: Chemistry and Biology",
publisher = "Springer Verlag",
pages = "149--162",
booktitle = "Detection of Biological Agents for the Prevention of Bioterrorism",
}