Abstract
Purpose: To describe scleral changes in chronic VKH. Methods: Medical records of patients with chronic VKH were retrospectively reviewed. Change of scleral architecture was defined as progressive posterior bowing on OCT, axial length elongation, and/or increased myopia more than –1.0 D, not explicable by other etiologies. Results: In total, 28 eyes (16 patients) with mean age of disease onset 32.5 ± 14.0 years were included in the study. Disease duration was 15.1 ± 10.2 years. Eight eyes (28.6%) showed progressive scleral architectural changes. Five eyes (18%) developed scleral changes on OCT, not seen on prior imaging (2–12 years earlier). One eye had posterior bowing on OCT with increased axial length, both eyes of a bilateral pseudophake developed increased myopia with increased axial length. Well-circumscribed chorioretinal atrophy within the arcade was associated with progressive scleral change. Conclusions: Progressive scleral change may develop as a late complication of VKH. The association with well-circumscribed chorioretinal atrophy suggests that chronic choroidal inflammation may be responsible.
Original language | English (US) |
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Pages (from-to) | 85-92 |
Number of pages | 8 |
Journal | Ocular Immunology and Inflammation |
Volume | 25 |
Issue number | 1 |
DOIs |
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State | Published - Jan 2 2017 |
Keywords
- OCT
- VKH
- choroid
- sclera
- uveitis
ASJC Scopus subject areas
- Immunology and Allergy
- Ophthalmology