Changes in sensitivity of vestibular nucleus neurons induced by cross-axis adaptation of the vestibulo-ocular reflex in the cat

Kevin J. Quinn; Janet O. Helminski; Allan J. Didier; James F. Baker; Barry W. Peterson

doi:10.1016/0006-8993(96)00013-3

Changes in sensitivity of vestibular nucleus neurons induced by cross-axis adaptation of the vestibulo-ocular reflex in the cat

Kevin J. Quinn^*, Janet O. Helminski, Allan J. Didier, James F. Baker, Barry W. Peterson

^*Corresponding author for this work

Physiology

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

In alert, chronically-prepared cats, we studied response characteristics of well-isolated vestibular nucleus neurons (n = 9) while pairing yaw rotation with a pitch optokinetic stimulus, resulting in cross-axis adaptation of the horizontal vestibulo-ocular reflex. Each neuron's sensitivity to whole body rotation in a variety of axes in three-dimensional space was determined. When tested in darkness following adaptation, neurons showed statistically significant increases in sensitivity to yaw but not vertical plane rotations, suggesting participation in reflex plasticity.

Original language	English (US)
Pages (from-to)	176-180
Number of pages	5
Journal	Brain research
Volume	718
Issue number	1-2
DOIs	https://doi.org/10.1016/0006-8993(96)00013-3
State	Published - Apr 29 1996

Keywords

Adaptation
Cross axis
Medial vestibular nucleus
Motor learning
Plasticity
Single unit
Superior vestibular nucleus
Vestibulo-ocular reflex

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

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10.1016/0006-8993(96)00013-3

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title = "Changes in sensitivity of vestibular nucleus neurons induced by cross-axis adaptation of the vestibulo-ocular reflex in the cat",

abstract = "In alert, chronically-prepared cats, we studied response characteristics of well-isolated vestibular nucleus neurons (n = 9) while pairing yaw rotation with a pitch optokinetic stimulus, resulting in cross-axis adaptation of the horizontal vestibulo-ocular reflex. Each neuron's sensitivity to whole body rotation in a variety of axes in three-dimensional space was determined. When tested in darkness following adaptation, neurons showed statistically significant increases in sensitivity to yaw but not vertical plane rotations, suggesting participation in reflex plasticity.",

keywords = "Adaptation, Cross axis, Medial vestibular nucleus, Motor learning, Plasticity, Single unit, Superior vestibular nucleus, Vestibulo-ocular reflex",

author = "Quinn, {Kevin J.} and Helminski, {Janet O.} and Didier, {Allan J.} and Baker, {James F.} and Peterson, {Barry W.}",

note = "Funding Information: This work was supported by NEI Grants EY06485, EY07342 and NINDS Grant NS31805. We thank Nancy Mockros for technical assistance.",

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doi = "10.1016/0006-8993(96)00013-3",

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T1 - Changes in sensitivity of vestibular nucleus neurons induced by cross-axis adaptation of the vestibulo-ocular reflex in the cat

AU - Quinn, Kevin J.

AU - Helminski, Janet O.

AU - Didier, Allan J.

AU - Baker, James F.

AU - Peterson, Barry W.

N1 - Funding Information: This work was supported by NEI Grants EY06485, EY07342 and NINDS Grant NS31805. We thank Nancy Mockros for technical assistance.

PY - 1996/4/29

Y1 - 1996/4/29

N2 - In alert, chronically-prepared cats, we studied response characteristics of well-isolated vestibular nucleus neurons (n = 9) while pairing yaw rotation with a pitch optokinetic stimulus, resulting in cross-axis adaptation of the horizontal vestibulo-ocular reflex. Each neuron's sensitivity to whole body rotation in a variety of axes in three-dimensional space was determined. When tested in darkness following adaptation, neurons showed statistically significant increases in sensitivity to yaw but not vertical plane rotations, suggesting participation in reflex plasticity.

AB - In alert, chronically-prepared cats, we studied response characteristics of well-isolated vestibular nucleus neurons (n = 9) while pairing yaw rotation with a pitch optokinetic stimulus, resulting in cross-axis adaptation of the horizontal vestibulo-ocular reflex. Each neuron's sensitivity to whole body rotation in a variety of axes in three-dimensional space was determined. When tested in darkness following adaptation, neurons showed statistically significant increases in sensitivity to yaw but not vertical plane rotations, suggesting participation in reflex plasticity.

KW - Adaptation

KW - Cross axis

KW - Medial vestibular nucleus

KW - Motor learning

KW - Plasticity

KW - Single unit

KW - Superior vestibular nucleus

KW - Vestibulo-ocular reflex

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Changes in sensitivity of vestibular nucleus neurons induced by cross-axis adaptation of the vestibulo-ocular reflex in the cat

Abstract

Keywords

ASJC Scopus subject areas

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