Changes in small dense low-density lipoprotein levels following acute coronary syndrome

Mahdi Reza Emadzadeh; Maryam Sadat Alavi; Mohammad Soukhtanloo; Toktam Mohammadpour; Amir Ali Rahsepar; Shima Tavallaie; Roshanak Khojasteh; Roghayeh Paydar; Maral Amini; Seyyed Mohammad Reza Parizadeh; Saeed Akhlaghi; Majid Ghayour-Mobarhan; Gordon A. Ferns

doi:10.1177/0003319712441855

Changes in small dense low-density lipoprotein levels following acute coronary syndrome

Mahdi Reza Emadzadeh, Maryam Sadat Alavi, Mohammad Soukhtanloo, Toktam Mohammadpour, Amir Ali Rahsepar, Shima Tavallaie, Roshanak Khojasteh, Roghayeh Paydar, Maral Amini, Seyyed Mohammad Reza Parizadeh, Saeed Akhlaghi, Majid Ghayour-Mobarhan^*, Gordon A. Ferns

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Low-density lipoprotein (LDL), especially small dense LDL (sdLDL), plays a role in atherogenesis. We compared baseline sdLDL levels between healthy controls and patients with acute coronary syndrome (ACS). Blood samples were taken from patients diagnosed with myocardial infarction ([MI] n = 104) and unstable angina ([UA] n = 100). Both sdLDL and high-sensitivity C-reactive protein (hsCRP) levels were determined on admission and in the next 24 hours after the onset of symptoms. Baseline concentration of sdLDL was significantly higher in patients presenting with ACS than controls (P <.05). In the 24 hours following ACS, the sdLDL levels decreased insignificantly in both groups of patients with ACS (P >.05). The changes in sdLDL values were not significantly different between MI and UA participants (P >.05). Patients with ACS have higher concentration of sdLDL compared with the controls.

Original language	English (US)
Pages (from-to)	216-222
Number of pages	7
Journal	Angiology
Volume	64
Issue number	3
DOIs	https://doi.org/10.1177/0003319712441855
State	Published - Apr 2013

Keywords

acute coronary syndrome
high-sensitive C-reactive protein
small dense low-density lipoprotein

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1177/0003319712441855

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Emadzadeh, M. R., Alavi, M. S., Soukhtanloo, M., Mohammadpour, T., Rahsepar, A. A., Tavallaie, S., Khojasteh, R., Paydar, R., Amini, M., Parizadeh, S. M. R., Akhlaghi, S., Ghayour-Mobarhan, M., & Ferns, G. A. (2013). Changes in small dense low-density lipoprotein levels following acute coronary syndrome. Angiology, 64(3), 216-222. https://doi.org/10.1177/0003319712441855

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abstract = "Low-density lipoprotein (LDL), especially small dense LDL (sdLDL), plays a role in atherogenesis. We compared baseline sdLDL levels between healthy controls and patients with acute coronary syndrome (ACS). Blood samples were taken from patients diagnosed with myocardial infarction ([MI] n = 104) and unstable angina ([UA] n = 100). Both sdLDL and high-sensitivity C-reactive protein (hsCRP) levels were determined on admission and in the next 24 hours after the onset of symptoms. Baseline concentration of sdLDL was significantly higher in patients presenting with ACS than controls (P <.05). In the 24 hours following ACS, the sdLDL levels decreased insignificantly in both groups of patients with ACS (P >.05). The changes in sdLDL values were not significantly different between MI and UA participants (P >.05). Patients with ACS have higher concentration of sdLDL compared with the controls.",

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AU - Rahsepar, Amir Ali

AU - Tavallaie, Shima

AU - Khojasteh, Roshanak

AU - Paydar, Roghayeh

AU - Amini, Maral

AU - Parizadeh, Seyyed Mohammad Reza

AU - Akhlaghi, Saeed

AU - Ghayour-Mobarhan, Majid

AU - Ferns, Gordon A.

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N2 - Low-density lipoprotein (LDL), especially small dense LDL (sdLDL), plays a role in atherogenesis. We compared baseline sdLDL levels between healthy controls and patients with acute coronary syndrome (ACS). Blood samples were taken from patients diagnosed with myocardial infarction ([MI] n = 104) and unstable angina ([UA] n = 100). Both sdLDL and high-sensitivity C-reactive protein (hsCRP) levels were determined on admission and in the next 24 hours after the onset of symptoms. Baseline concentration of sdLDL was significantly higher in patients presenting with ACS than controls (P <.05). In the 24 hours following ACS, the sdLDL levels decreased insignificantly in both groups of patients with ACS (P >.05). The changes in sdLDL values were not significantly different between MI and UA participants (P >.05). Patients with ACS have higher concentration of sdLDL compared with the controls.

AB - Low-density lipoprotein (LDL), especially small dense LDL (sdLDL), plays a role in atherogenesis. We compared baseline sdLDL levels between healthy controls and patients with acute coronary syndrome (ACS). Blood samples were taken from patients diagnosed with myocardial infarction ([MI] n = 104) and unstable angina ([UA] n = 100). Both sdLDL and high-sensitivity C-reactive protein (hsCRP) levels were determined on admission and in the next 24 hours after the onset of symptoms. Baseline concentration of sdLDL was significantly higher in patients presenting with ACS than controls (P <.05). In the 24 hours following ACS, the sdLDL levels decreased insignificantly in both groups of patients with ACS (P >.05). The changes in sdLDL values were not significantly different between MI and UA participants (P >.05). Patients with ACS have higher concentration of sdLDL compared with the controls.

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Changes in small dense low-density lipoprotein levels following acute coronary syndrome

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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