Changes in the effects of stimulation of locus coeruleus and nucleus raphe magnus following dorsal rhizotomy

Charles J. Hodge*, A. Vania Apkarian, Michael P. Owen, Brian S. Hanson

*Corresponding author for this work

Research output: Contribution to journalArticle

51 Scopus citations

Abstract

The effects of stimulating locus coeruleus (LC) and nucleus raphe magnus (NRM) on lumbar dorsal horn cells that had been denervated by dorsal rhizotomy were studied. Both LC and NRM stimulation inhibited the responses of dorsal horn cells from the side of the cord with intact dorsal roots. However, when cells from the side of the spinal cord that had had prior rhizotomies were studies, half of the units were shown to be activated by either LC or NRM stimulation.

Original languageEnglish (US)
Pages (from-to)325-329
Number of pages5
JournalBrain research
Volume288
Issue number1-2
DOIs
StatePublished - Dec 12 1983

Keywords

  • deafferentation
  • dorsal horn
  • locus coeruleus
  • nucleus raphe magnus

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'Changes in the effects of stimulation of locus coeruleus and nucleus raphe magnus following dorsal rhizotomy'. Together they form a unique fingerprint.

  • Cite this