Abstract
The effects of stimulating locus coeruleus (LC) and nucleus raphe magnus (NRM) on lumbar dorsal horn cells that had been denervated by dorsal rhizotomy were studied. Both LC and NRM stimulation inhibited the responses of dorsal horn cells from the side of the cord with intact dorsal roots. However, when cells from the side of the spinal cord that had had prior rhizotomies were studies, half of the units were shown to be activated by either LC or NRM stimulation.
Original language | English (US) |
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Pages (from-to) | 325-329 |
Number of pages | 5 |
Journal | Brain research |
Volume | 288 |
Issue number | 1-2 |
DOIs | |
State | Published - Dec 12 1983 |
Funding
This work was supported in part by a gift from the Perkins Foundation. We thank Norma Horton for expert histologic assistance.
Keywords
- deafferentation
- dorsal horn
- locus coeruleus
- nucleus raphe magnus
ASJC Scopus subject areas
- Clinical Neurology
- Molecular Biology
- General Neuroscience
- Developmental Biology