Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study

Ariane Mamguem Kamga; Samiratou Ouédraogo; Firmin Nongodo Kaboré; Isidore Tiandiogo Traoré; Esperance Ouédraogo; Armel Poda; Arnaud Eric Diendéré; Dramane Kania; Hermann Badolo; Guillaume Sanou; Amariane Koné; Therese Samdapawindé Kagoné; Blahima Konaté; Rachel Médah; Nathalie de Rekeneire; Boukary Ouédraogo; Oumar Billa; Gilles Paradis; Halidou Tinto; Tienhan Sandrine Dabakuyo-yonli

doi:10.3389/fpubh.2025.1542024

Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study

Ariane Mamguem Kamga^*, Samiratou Ouédraogo, Firmin Nongodo Kaboré, Isidore Tiandiogo Traoré, Esperance Ouédraogo, Armel Poda, Arnaud Eric Diendéré, Dramane Kania, Hermann Badolo, Guillaume Sanou, Amariane Koné, Therese Samdapawindé Kagoné, Blahima Konaté, Rachel Médah, Nathalie de Rekeneire, Boukary Ouédraogo, Oumar Billa, Gilles Paradis, Halidou Tinto, Tienhan Sandrine Dabakuyo-yonli

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Objectives: To assess treatment and identify predictive factors of worsening in COVID-19 patients. Methods: This study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data about the COVID-19 epidemic in Burkina Faso. Medical records of patients admitted for COVID-19 at the hospitals of Ouagadougou and Bobo-Dioulasso from March 2020 to April 2021 were reviewed. To identify predictive factors of severe complications, we used Poisson regression models. Results: In total, 1,511 patients were included, of whom 70% were aged ≤50 years, 59% were men and 97% were living in an urban area. Of the 86% of patients treated, 92.9% of them received the combo Azithromycin-hydroxychloroquine. A total of 78 (5.2%) patients experienced complications during hospitalization, and 49 (3.3%) patients died. Multivariate analysis identified patient's age, residence and comorbidity as factors associated with poor outcomes. Conclusions: Although most people had symptoms, most of them recovered without sequelae, and few patients had severe forms of disease. Age was a strong predictor of worse outcomes in this population.

Original language	English (US)
Article number	1542024
Journal	Frontiers in Public Health
Volume	13
DOIs	https://doi.org/10.3389/fpubh.2025.1542024
State	Published - 2025
Externally published	Yes

Funding

The author(s) declare that financial support was received for the research and/or publication of this article. This project was supported by the ANRS (France REcherche Nord & Sud Sida-hiv-Hépatites) [ANRS-COV13/EMuLCOVID-19]. The funding bodies was not involved in the study design, collection, analysis, and interpretation of data, the writing of this article or the decision to submit it for publication.

Keywords

COVID-19
age
comorbidity
complications
treatment

ASJC Scopus subject areas

Public Health, Environmental and Occupational Health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3389/fpubh.2025.1542024

Cite this

Mamguem Kamga, A., Ouédraogo, S., Kaboré, F. N., Traoré, I. T., Ouédraogo, E., Poda, A., Diendéré, A. E., Kania, D., Badolo, H., Sanou, G., Koné, A., Kagoné, T. S., Konaté, B., Médah, R., Rekeneire, N. D., Ouédraogo, B., Billa, O., Paradis, G., Tinto, H., & Dabakuyo-yonli, T. S. (2025). Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study. Frontiers in Public Health, 13, Article 1542024. https://doi.org/10.3389/fpubh.2025.1542024

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title = "Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study",

abstract = "Objectives: To assess treatment and identify predictive factors of worsening in COVID-19 patients. Methods: This study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data about the COVID-19 epidemic in Burkina Faso. Medical records of patients admitted for COVID-19 at the hospitals of Ouagadougou and Bobo-Dioulasso from March 2020 to April 2021 were reviewed. To identify predictive factors of severe complications, we used Poisson regression models. Results: In total, 1,511 patients were included, of whom 70\% were aged ≤50 years, 59\% were men and 97\% were living in an urban area. Of the 86\% of patients treated, 92.9\% of them received the combo Azithromycin-hydroxychloroquine. A total of 78 (5.2\%) patients experienced complications during hospitalization, and 49 (3.3\%) patients died. Multivariate analysis identified patient's age, residence and comorbidity as factors associated with poor outcomes. Conclusions: Although most people had symptoms, most of them recovered without sequelae, and few patients had severe forms of disease. Age was a strong predictor of worse outcomes in this population.",

keywords = "COVID-19, age, comorbidity, complications, treatment",

author = "\{Mamguem Kamga\}, Ariane and Samiratou Ou{\'e}draogo and Kabor{\'e}, \{Firmin Nongodo\} and Traor{\'e}, \{Isidore Tiandiogo\} and Esperance Ou{\'e}draogo and Armel Poda and Diend{\'e}r{\'e}, \{Arnaud Eric\} and Dramane Kania and Hermann Badolo and Guillaume Sanou and Amariane Kon{\'e} and Kagon{\'e}, \{Therese Samdapawind{\'e}\} and Blahima Konat{\'e} and Rachel M{\'e}dah and Rekeneire, \{Nathalie de\} and Boukary Ou{\'e}draogo and Oumar Billa and Gilles Paradis and Halidou Tinto and Dabakuyo-yonli, \{Tienhan Sandrine\}",

note = "Publisher Copyright: Copyright {\textcopyright} 2025 Mamguem Kamga, Ou{\'e}draogo, Kabor{\'e}, Traor{\'e}, Ou{\'e}draogo, Poda, Diend{\'e}r{\'e}, Kania, Badolo, Sanou, Kon{\'e}, Kagon{\'e}, Konat{\'e}, M{\'e}dah, Rekeneire, Ou{\'e}draogo, Billa, Paradis, Tinto and Dabakuyo-yonli.",

year = "2025",

doi = "10.3389/fpubh.2025.1542024",

language = "English (US)",

volume = "13",

journal = "Frontiers in Public Health",

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Mamguem Kamga, A, Ouédraogo, S, Kaboré, FN, Traoré, IT, Ouédraogo, E, Poda, A, Diendéré, AE, Kania, D, Badolo, H, Sanou, G, Koné, A, Kagoné, TS, Konaté, B, Médah, R, Rekeneire, ND, Ouédraogo, B, Billa, O, Paradis, G, Tinto, H & Dabakuyo-yonli, TS 2025, 'Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study', Frontiers in Public Health, vol. 13, 1542024. https://doi.org/10.3389/fpubh.2025.1542024

TY - JOUR

T1 - Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso

T2 - insights from a 2021 large-scale ambispective study

AU - Mamguem Kamga, Ariane

AU - Ouédraogo, Samiratou

AU - Kaboré, Firmin Nongodo

AU - Traoré, Isidore Tiandiogo

AU - Ouédraogo, Esperance

AU - Poda, Armel

AU - Diendéré, Arnaud Eric

AU - Kania, Dramane

AU - Badolo, Hermann

AU - Sanou, Guillaume

AU - Koné, Amariane

AU - Kagoné, Therese Samdapawindé

AU - Konaté, Blahima

AU - Médah, Rachel

AU - Rekeneire, Nathalie de

AU - Ouédraogo, Boukary

AU - Billa, Oumar

AU - Paradis, Gilles

AU - Tinto, Halidou

AU - Dabakuyo-yonli, Tienhan Sandrine

N1 - Publisher Copyright: Copyright © 2025 Mamguem Kamga, Ouédraogo, Kaboré, Traoré, Ouédraogo, Poda, Diendéré, Kania, Badolo, Sanou, Koné, Kagoné, Konaté, Médah, Rekeneire, Ouédraogo, Billa, Paradis, Tinto and Dabakuyo-yonli.

PY - 2025

Y1 - 2025

N2 - Objectives: To assess treatment and identify predictive factors of worsening in COVID-19 patients. Methods: This study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data about the COVID-19 epidemic in Burkina Faso. Medical records of patients admitted for COVID-19 at the hospitals of Ouagadougou and Bobo-Dioulasso from March 2020 to April 2021 were reviewed. To identify predictive factors of severe complications, we used Poisson regression models. Results: In total, 1,511 patients were included, of whom 70% were aged ≤50 years, 59% were men and 97% were living in an urban area. Of the 86% of patients treated, 92.9% of them received the combo Azithromycin-hydroxychloroquine. A total of 78 (5.2%) patients experienced complications during hospitalization, and 49 (3.3%) patients died. Multivariate analysis identified patient's age, residence and comorbidity as factors associated with poor outcomes. Conclusions: Although most people had symptoms, most of them recovered without sequelae, and few patients had severe forms of disease. Age was a strong predictor of worse outcomes in this population.

AB - Objectives: To assess treatment and identify predictive factors of worsening in COVID-19 patients. Methods: This study was ambispective (both prospective and retrospective) and part of a multidisciplinary, multicenter project designed to generate epidemiological, sociological and anthropological data about the COVID-19 epidemic in Burkina Faso. Medical records of patients admitted for COVID-19 at the hospitals of Ouagadougou and Bobo-Dioulasso from March 2020 to April 2021 were reviewed. To identify predictive factors of severe complications, we used Poisson regression models. Results: In total, 1,511 patients were included, of whom 70% were aged ≤50 years, 59% were men and 97% were living in an urban area. Of the 86% of patients treated, 92.9% of them received the combo Azithromycin-hydroxychloroquine. A total of 78 (5.2%) patients experienced complications during hospitalization, and 49 (3.3%) patients died. Multivariate analysis identified patient's age, residence and comorbidity as factors associated with poor outcomes. Conclusions: Although most people had symptoms, most of them recovered without sequelae, and few patients had severe forms of disease. Age was a strong predictor of worse outcomes in this population.

KW - COVID-19

KW - age

KW - comorbidity

KW - complications

KW - treatment

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U2 - 10.3389/fpubh.2025.1542024

DO - 10.3389/fpubh.2025.1542024

M3 - Article

C2 - 40709029

AN - SCOPUS:105011347051

SN - 2296-2565

VL - 13

JO - Frontiers in Public Health

JF - Frontiers in Public Health

M1 - 1542024

ER -

Characteristics, management and factors associated with poor outcomes in COVID-19 patients in Burkina Faso: insights from a 2021 large-scale ambispective study

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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