Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene

F. Valle; G. Gosset; B. Tenorio; G. Oliver; F. Bolivar

doi:10.1016/0378-1119(86)90316-1

Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene

F. Valle, G. Gosset, B. Tenorio, G. Oliver, F. Bolivar^*

^*Corresponding author for this work

Medicine, Nephrology Division

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Penicillin acylase is utilized in the enzymatic production of semisynthetic penicillins. The enzyme is composed of two different subunits that originate from a common precursor. The partial nucleotide (nt) sequence of the structural gene has been published. This paper reports the nt sequence of the regulatory region of this gene, the identification of a functional promoter, the transcriptional start point, and the description of possible regulatory regions.

Original language	English (US)
Pages (from-to)	119-122
Number of pages	4
Journal	Gene
Volume	50
Issue number	1-3
DOIs	https://doi.org/10.1016/0378-1119(86)90316-1
State	Published - 1986

Keywords

Nucleotide sequence
primer extension
promoter identification

ASJC Scopus subject areas

Genetics

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10.1016/0378-1119(86)90316-1

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abstract = "Penicillin acylase is utilized in the enzymatic production of semisynthetic penicillins. The enzyme is composed of two different subunits that originate from a common precursor. The partial nucleotide (nt) sequence of the structural gene has been published. This paper reports the nt sequence of the regulatory region of this gene, the identification of a functional promoter, the transcriptional start point, and the description of possible regulatory regions.",

keywords = "Nucleotide sequence, primer extension, promoter identification",

author = "F. Valle and G. Gosset and B. Tenorio and G. Oliver and F. Bolivar",

year = "1986",

doi = "10.1016/0378-1119(86)90316-1",

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T1 - Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene

AU - Valle, F.

AU - Gosset, G.

AU - Tenorio, B.

AU - Oliver, G.

AU - Bolivar, F.

PY - 1986

Y1 - 1986

N2 - Penicillin acylase is utilized in the enzymatic production of semisynthetic penicillins. The enzyme is composed of two different subunits that originate from a common precursor. The partial nucleotide (nt) sequence of the structural gene has been published. This paper reports the nt sequence of the regulatory region of this gene, the identification of a functional promoter, the transcriptional start point, and the description of possible regulatory regions.

AB - Penicillin acylase is utilized in the enzymatic production of semisynthetic penicillins. The enzyme is composed of two different subunits that originate from a common precursor. The partial nucleotide (nt) sequence of the structural gene has been published. This paper reports the nt sequence of the regulatory region of this gene, the identification of a functional promoter, the transcriptional start point, and the description of possible regulatory regions.

KW - Nucleotide sequence

KW - primer extension

KW - promoter identification

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U2 - 10.1016/0378-1119(86)90316-1

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JO - Gene

JF - Gene

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IS - 1-3

ER -

Characterization of the regulatory region of the Escherichia coli penicillin acylase structural gene

Abstract

Keywords

ASJC Scopus subject areas

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