Characterization of the tendon vibration reflex response in hemi-spastic stroke individuals

Nina L. Suresh*, Inga Wang, C. J. Heckman, W. Zev Rymer

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

The objective of our study was to assess the role of persistent inward currents, or PICs, on the excitability of motoneurons innervating spastic muscle in hemi-spastic stroke individuals. This was accomplished by examining the effects of tonic vibration applied to the tendon of the biceps brachii muscle. The elicited TVR (tonic vibration reflex) provides a useful way to assess the degree of excitability of spinal neurons in spastic syndromes, and it has additional features that may signify the presence of PICs in spastic motoneurons. We applied sinusoidal stretches of varied duration to the biceps tendon of two hemi-spastic stroke individuals and one neurologically intact individual. We recorded the resulting TVR response from electromyographic(EMG) signals obtained from the biceps as well as force recorded at the wrist. The results of our preliminary study show that the initial rise of the TVR force response as well as the force magnitude are generally greater in spastic muscle, perhaps a marker of motoneuron excitability. Additionally, a shorter vibration duration was sufficient to evoke a response on the spastic side of our tested stroke subjects. However, the key marker of PICs the decay of the force response as well as sustained after-discharge did not exhibit clear differences. Our present data suggests that motoneurons innervating spastic muscle are more readily activated, and thus exhibit increased excitability, which could possibly be a function of greater depolarization, without a change in PIC magnitude. Our data does not rule out the possibility of subthreshold activation of the PIC resulting in enhanced motoneuron depolarization.

Original languageEnglish (US)
Title of host publication33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
Pages2053-2056
Number of pages4
DOIs
StatePublished - 2011
Event33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States
Duration: Aug 30 2011Sep 3 2011

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Other

Other33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011
CountryUnited States
CityBoston, MA
Period8/30/119/3/11

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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    Suresh, N. L., Wang, I., Heckman, C. J., & Rymer, W. Z. (2011). Characterization of the tendon vibration reflex response in hemi-spastic stroke individuals. In 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 (pp. 2053-2056). [6090379] (Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS). https://doi.org/10.1109/IEMBS.2011.6090379