Charge receombination in DNA hairpins controlled by counterions

Gail S. Blaustein, Brittany Demas, Frederick D. Lewis, Alexander L. Burin

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

The slow charge recombination in DNA hairpins of various lengths is investigated. The distance dependence for the charge recombination rate between stilbene donor (Sd+) and stilbene acceptor (Sa-) linkers separated by AT bridges of various lengths has the double exponential form. We suggest that this puzzling dependence is associated with two tunneling channels distinguished by the presence or absence of a Cl- counterion bound to an Sd+ linker. When Cl- is associated with Sd+ the energy of positive charge is lower compared to Sd+ without a counterion. Therefore the potential barrier for charge recombination is higher in the presence of Cl- bound to Sd+, and the recombination is characterized by the larger tunneling exponent than the tunneling exponent in the absence of counterions. Experimentbased estimates of binding parameters agree within reasonable expectations. The control experiment replacing the Cl- ion with other ions is suggested. This replacement enables the control of the charge recombination rate modifying it in either direction by orders of magnitude.

Original languageEnglish (US)
Pages (from-to)400-401
Number of pages2
JournalJournal of the American Chemical Society
Volume131
Issue number2
DOIs
StatePublished - Jan 21 2009

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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