Chemotherapy: What is its role in meningioma?

W. J. Sherman, J. J. Raizer*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations

Abstract

While strong evidence exists for the standard therapy for meningiomas, inclusive of surgery and/or radiation therapy, for those tumors which recur, progress or are inoperable, the optimal medical therapies are yet to be elucidated. This article reviews the current literature for chemotherapeutic options for this subset of tumors, including cytotoxic agents, biologic agents, targeted molecular agents and hormonal agents. At this point in time, the most data is with hydroxyurea and somatostatin, although further trials with combination and targeted molecular therapies are still underway.

Original languageEnglish (US)
Pages (from-to)1189-1196
Number of pages8
JournalExpert Review of Neurotherapeutics
Volume12
Issue number10
DOIs
StatePublished - Oct 2012

Keywords

  • IFN-a
  • bevacizumab
  • chemotherapy
  • erlotinib
  • gefitinib
  • hydroxyurea
  • imatinib mesylate
  • meningioma
  • mifepristone
  • octreotide
  • somatostatin
  • tamoxifen

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology
  • Pharmacology (medical)

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