Childhood ovarian cancers. New advances in treatment

M. S. Piver, J. Lurain

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


From 1968 to 1978, 30 patients, age 4 to 20, with ovarian malignant growths were admitted to Roswell Park Memorial Institute. Recent advances in the treatment of childhood ovarian cancers have led to a significant improvement in survival rates. These therapeutic modalities include whole abdominal irradiation with or without mediastinal and left supraclavicular irradiation in children with ovarian dysgerminoma, the use of vincristine sulfate, actinomycin-D, and cyclophosphamide as adjunctive therapy in children with stage IA immature teratoma or endodermal sinus tumor, and high-dose methotrexate plus cyclophosphamide in metastatic epithelial ovarian cancer. In children with a unilateral ovarian stromal tumor, conservative surgery with preservation of future child-bearing potential should be carried out.

Original languageEnglish (US)
Pages (from-to)1196-1199
Number of pages4
JournalNew York State Journal of Medicine
Issue number8
StatePublished - Dec 1 1979

ASJC Scopus subject areas

  • General Medicine


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