TY - JOUR
T1 - Chinese herbal medicine increases tissue oxygen tension.
AU - Linsenmeier, R. A.
AU - Goldstick, T. K.
AU - Zhang, S. L.
PY - 1989
Y1 - 1989
N2 - An herbal medicine widely used in China, anisodamine, was investigated to determine its effect on the tissue PO2 of an important neural tissue, the retina. The anisodamine was injected intravenously over 10 min into anesthetized cats. Although it reduced mean blood pressure an average of 26%, anisodamine simultaneously increased tissue PO2 an average of 20%. It may therefore be useful in treating clinical conditions thought to be secondary to tissue hypoxia, such as diabetic retinopathy and sickle cell crises.
AB - An herbal medicine widely used in China, anisodamine, was investigated to determine its effect on the tissue PO2 of an important neural tissue, the retina. The anisodamine was injected intravenously over 10 min into anesthetized cats. Although it reduced mean blood pressure an average of 26%, anisodamine simultaneously increased tissue PO2 an average of 20%. It may therefore be useful in treating clinical conditions thought to be secondary to tissue hypoxia, such as diabetic retinopathy and sickle cell crises.
UR - http://www.scopus.com/inward/record.url?scp=0024326361&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024326361&partnerID=8YFLogxK
U2 - 10.1007/978-1-4684-5643-1_90
DO - 10.1007/978-1-4684-5643-1_90
M3 - Article
C2 - 2782189
AN - SCOPUS:0024326361
SN - 0065-2598
VL - 248
SP - 795
EP - 801
JO - Advances in experimental medicine and biology
JF - Advances in experimental medicine and biology
ER -
