Chiral cyclohexane 1,3-diones as inhibitors of mutant SOD1-dependent protein aggregation for the treatment of ALS

Yinan Zhang, Radhia Benmohamed, Wei Zhang, Jinho Kim, Christina K. Edgerly, Yaoqiu Zhu, Richard I. Morimoto, Robert J. Ferrante, Donald R. Kirsch, Richard B. Silverman*

*Corresponding author for this work

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Neuroscience

Pharmacology, Toxicology and Pharmaceutical Science