Chlamydia specific IgG and IgA serum antibodies in a study of homosexual men at various clinical stages of HIV related disease

B. Sarov, A. J. Saah, E. Levy, S. Elsana, I. Sarov, C. R. Rinaldo, R. Detels, J. Phair, R. Kaslow, H. Gisnberg, M. Margalith*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

The significance of chlamydia serum IgG and IgA antibodies was studied, by immunoperoxidase assay, in 210 homosexual men at various stages of HIV infection. Cross sectional analysis of chlamydia IgG antibodies at a titer of ≥ 128 indicated a significantly higher prevalence rate among AIDS patients (27.0%) as compared to asymptomatic HIV seronegatives (6.0%) (p = 0.022). The geometric mean titer (GMT) of IgG antibodies to chlamydia was also significantly higher in AIDS patients (106.4) as compared to HIV seronegatives (58.2) (p = 0.022) and persistently asymptomatic HIV seropositives (51.7) (p = 0.05). Chlamydia IgA antibodies did not differ significantly in prevalence and GMT among the various groups.

Original languageEnglish (US)
Pages (from-to)593-597
Number of pages5
JournalIn Vivo
Volume8
Issue number4
StatePublished - Jan 1 1994

Keywords

  • AIDS
  • Chlamydia
  • HIV
  • IgG and IgA antibodies

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology

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