Choline acetyltransferase-like immunoreactivity in the forebrain of the red-eared pond turtle (Pseudemys scripta elegans)

E. J. Mufson*, P. H. Desan, M. M. Mesulam, B. H. Wainer, A. I. Levey

*Corresponding author for this work

Research output: Contribution to journalArticle

57 Scopus citations

Abstract

Choline acetyltransferase (ChAT) immunohistochemistry was used to map the cholinergic neurons in the forebrain of Pseudemys turtles. Cell bodies with ChAT-like immunoreactivity were seen in the septum, the nucleus of the diagonal band, and embedded within the medial and lateral forebrain bundles. The region of the medial and lateral forebrain bundles contained the greatest concentration of ChAT-positive neurons. Virtually no ChAT-like immunoreactivity was seen in the areas composing the reptilian homologue of the mammalian striatum. It is suggested that the turtle basal forebrain cholinergic neurons may represent the evolutionary precursors to the mammalian cholinergic neurons of the basal forebrain and even the striatum.

Original languageEnglish (US)
Pages (from-to)103-108
Number of pages6
JournalBrain research
Volume323
Issue number1
DOIs
StatePublished - Dec 3 1984

Keywords

  • basal forebrain
  • choline acetyltransferase
  • cholinergic
  • immunohistochemistry
  • turtle

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

Fingerprint Dive into the research topics of 'Choline acetyltransferase-like immunoreactivity in the forebrain of the red-eared pond turtle (Pseudemys scripta elegans)'. Together they form a unique fingerprint.

  • Cite this