Cholinesterases within neurofibrillary tangles related to age and Alzheimer's disease

M‐Marsel ‐M Mesulam*, M. Asuncion Morán

*Corresponding author for this work

Research output: Contribution to journalArticle

100 Scopus citations

Abstract

Enzyme histochemistry showed that a substantial number of cortical neurofibrillary tangles contain acetylcholinesterase and butyrylcholinesterase activities in patients with Alzheimer's disease and in nondemented aged individuals. In some areas of the brain, tangles containing each of these two enzymes were differentially distributed. In other areas, there was a very close overlap between the two types of cholinesterase.

Original languageEnglish (US)
Pages (from-to)223-228
Number of pages6
JournalAnnals of neurology
Volume22
Issue number2
DOIs
StatePublished - Aug 1987

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Cholinesterases within neurofibrillary tangles related to age and Alzheimer's disease'. Together they form a unique fingerprint.

  • Cite this