TY - JOUR
T1 - Chondroma/Chondrosarcoma of the Spine
AU - McLoughlin, Gregory S.
AU - Sciubba, Daniel M.
AU - Wolinsky, Jean Paul
PY - 2008/1
Y1 - 2008/1
N2 - Chondromas and chondrosarcomas are cartilage-forming tumors that occur rarely in the spine. These neoplasms exist on opposite ends of the pathologic spectrum, ranging from the benign chondroma to the malignant, high-grade chondrosarcoma. Unlike other sarcomas, a patient's long-term prognosis is influenced by the grade of the tumor. A complete en bloc resection is the ideal method of surgical management. This method holds especially true for chondrosarcomas, and can result in prolonged survival. These tumors are resistant to conventional chemotherapy and radiation therapy. Hypofractionated stereotactic radiation therapy may slow tumor progression, although the long-term effect of this modality is unknown.
AB - Chondromas and chondrosarcomas are cartilage-forming tumors that occur rarely in the spine. These neoplasms exist on opposite ends of the pathologic spectrum, ranging from the benign chondroma to the malignant, high-grade chondrosarcoma. Unlike other sarcomas, a patient's long-term prognosis is influenced by the grade of the tumor. A complete en bloc resection is the ideal method of surgical management. This method holds especially true for chondrosarcomas, and can result in prolonged survival. These tumors are resistant to conventional chemotherapy and radiation therapy. Hypofractionated stereotactic radiation therapy may slow tumor progression, although the long-term effect of this modality is unknown.
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U2 - 10.1016/j.nec.2007.09.007
DO - 10.1016/j.nec.2007.09.007
M3 - Review article
C2 - 18156048
AN - SCOPUS:37349005879
SN - 1042-3680
VL - 19
SP - 57
EP - 63
JO - Neurosurgery clinics of North America
JF - Neurosurgery clinics of North America
IS - 1
ER -