Choreoathetosis in the setting of lithium toxicity

Background: Lithium toxicity has been shown to cause lasting neurological sequelae in certain cases. Objective: The authors present a case of choreoathetosis in the aftermath of a presumed episode of lithium toxic reaction. Method: The patient was treated by aggressive rehydration; lithium and, ultimately, all psychotropic medication was withheld for a period. Results: The patient showed marked improvement in orientation and movement control; however, some of the choreoathetoid symptoms persisted. Conclusion: Patients on combination therapy with lithium and other psychotropics need to be closely monitored for the development of choreoathetoid and other symptoms of overmedication.