Choroidal occlusive disease in sickle cell hemoglobinopathies

Rutheva V. Dizon, Lee M. Jampol*, Morton F. Goldberg, Claudio Juarez

*Corresponding author for this work

Research output: Contribution to journalReview article

23 Scopus citations

Abstract

Two distinct episodes of posterior ciliary artery occlusion were studied in a 32-year-old man with hemoglobin SS disease and multiple episodes of amaurosis fugax. Although posterior ciliary artery occlusions have been observed following photocoagulation of sickle cell retinopathy, their spontaneous evolution in patients with sickling hemoglobinopathies has received little attention. The manifestations of posterior ciliary artery occlusion seen in this case and in other clinical and experimental situations are reviewed. Histopathologic examination of three additional eyes of patients with sickle hemoglobinopathies revealed changes which may have been the result of previous small posterior ciliary artery occlusions or small vessel occulusive disease related to the sickling hemoglobinopathies; these cases are also reported.

Original languageEnglish (US)
Pages (from-to)297-306
Number of pages10
JournalSurvey of ophthalmology
Volume23
Issue number5
DOIs
StatePublished - Jan 1 1979

Keywords

  • amaurosis fugax
  • choriocapillaris
  • choroid
  • ischemia
  • lesions
  • posterior ciliary artery
  • sickle cell disease

ASJC Scopus subject areas

  • Ophthalmology

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