Chromatin hubs drive key regulatory networks in leukemia

Alok Swaroop; Feng Yue

doi:10.1016/j.molcel.2024.12.011

Chromatin hubs drive key regulatory networks in leukemia

Alok Swaroop, Feng Yue^*

^*Corresponding author for this work

Biochemistry and Molecular Genetics

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

In this issue of Molecular Cell, Gambi, Boccalatte, Hernaez, et al.¹ apply multiomics followed by genetic engineering to define then characterize epigenetic hubs that regulate processes crucial for T-ALL and use this insight to offer new avenues for therapeutic targeting.

Original language	English (US)
Pages (from-to)	1-2
Number of pages	2
Journal	Molecular cell
Volume	85
Issue number	1
DOIs	https://doi.org/10.1016/j.molcel.2024.12.011
State	Published - Jan 2 2025

Funding

The Yue lab is supported by is supported by United States National Institute of Health grants R35GM124820 and R01HG011207.

ASJC Scopus subject areas

Molecular Biology
Cell Biology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.molcel.2024.12.011

Cite this

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title = "Chromatin hubs drive key regulatory networks in leukemia",

abstract = "In this issue of Molecular Cell, Gambi, Boccalatte, Hernaez, et al.1 apply multiomics followed by genetic engineering to define then characterize epigenetic hubs that regulate processes crucial for T-ALL and use this insight to offer new avenues for therapeutic targeting.",

author = "Alok Swaroop and Feng Yue",

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year = "2025",

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AB - In this issue of Molecular Cell, Gambi, Boccalatte, Hernaez, et al.1 apply multiomics followed by genetic engineering to define then characterize epigenetic hubs that regulate processes crucial for T-ALL and use this insight to offer new avenues for therapeutic targeting.

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DO - 10.1016/j.molcel.2024.12.011

M3 - Comment/debate

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SN - 1097-2765

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Chromatin hubs drive key regulatory networks in leukemia

Abstract

Funding

ASJC Scopus subject areas

UN SDGs

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