Chronic activation of protein kinase Bβ/Akt2 leads to multinucleation and cell fusion in human epithelial kidney cells: Events associated with tumorigenesis

Keyphrases

• 4-hydroxytamoxifen 50%
• AKT2 100%
• Angiogenesis 50%
• Autophagy 50%
• Cancer Development 50%
• Cell Behavior 50%
• Cell Cycle Progression 50%
• Cell Fusion 100%
• Cell Motility 50%
• Cell Survival 50%
• Cellular Events 100%
• Cellular Growth 50%
• Chromosome Complement 50%
• Endomitosis 50%
• Estrogen Receptor Ligands 50%
• Estrogen Receptor Status 50%
• Genetic Changes 50%
• Genomic Instability 100%
• HEK293 50%
• Human Kidney 50%
• Kidney Cells 100%
• Kidney Epithelial Cells 50%
• Ligand-binding Domain 50%
• Malignant Process 50%
• Multinucleation 100%
• Oncogene 50%
• Phosphoinositide 3-kinase (PI3K) 50%
• Protein Kinase B 100%
• Protein Kinase B (PKB)/Akt 50%
• Receptor-ligand Binding 50%
• Tumor Cells 50%
• Tumorigenesis 100%

Medicine and Dentistry

• Afimoxifene 50%
• Aneuploidy 50%
• Angiogenesis 50%
• Autophagy 50%
• Carcinogenesis 100%
• Cell Cycle Progression 50%
• Cell Function 50%
• Cell Fusion 100%
• Cell Growth 50%
• Cell Migration 50%
• Cell Motility 50%
• Cell Survival 50%
• Epithelial Cell 50%
• Estrogen Receptor 100%
• Gene Mutation 50%
• Kidney Cell 100%
• Ligand Binding 50%
• Malignant Neoplasm 100%
• Phosphoinositide 3-Kinase 50%
• Protein Kinase B 100%
• Proto Oncogene 50%
• Tumor Cell 50%

Biochemistry, Genetics and Molecular Biology

• Angiogenesis 50%
• Autophagy 50%
• Carcinogenesis 100%
• Cell Cycle Progression 50%
• Cell Function 50%
• Cell Fusion 100%
• Cell Growth 50%
• Cell Migration 50%
• Cell Motility 50%
• Cell Survival 50%
• Estrogen Receptor 100%
• Gene Mutation 50%
• Genetics 100%
• Ligand Binding Domain 50%
• Phosphoinositide 3-Kinase 50%
• Protein Kinase B 100%
• Proto Oncogene 50%
• Transcription 50%