Chronic recurrent multiple evanescent white dot syndrome

Purpose: Multiple evanescent white dot syndrome (MEWDS) is usually unilateral, self-limited, and monophasic. The purpose of this study was to demonstrate that a chronic recurring form of the disease exists. Methods: Three patients with otherwise typical MEWDS were observed for 4 to 5 years. Their ocular histories and physical findings were recorded. Results: Multiple recurrences (5-7) involving both eyes were noted in each of the three patients. Classic clinical findings were seen, including granularity to the macula, white dots, and optic disc changes. Despite these recurrences, the patients still retained visual acuity of 20/20 in each eye. Conclusion: A chronic recurrent form of MEWDS exists. The cause of MEWDS remains unknown, and it is unclear why these patients demonstrated this atypical clinical course.