Cicatricial Pemphigoid in a 6‐Year‐Old Child: Report of a Case and Review of the Literature

Marjorie Mintz Rosenbaum*, Nancy Burton Esterly, Mark J. Greenwald, Carol Roberts Gerson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Abstract: Cicatricial pemphigoid has been documented previously in only four patients under the age of 20 years. We report a 6‐year‐old male who had erosions of the oral and genital mucosa, conjunctivitis, hoarseness, dysphagia, recurrent vomiting, and weight loss. Upper airway obstruction due to a chronically inflamed and scarred epiglottis necessitated tracheostomy. Biopsy of tissue from a solitary cutaneous lesion demonstrated a subepidennal bulla. Direct and indirect immunofluorescence confirmed a diagnosis of cicatricial pemphigoid. Therapy was begun consisting of prednisone, 2 mg per kg per day, in combination with dapsone, 2 mg per kg per day. He did not improve until the prednisone dosage was increased to 4 mg per kg per day.

Original languageEnglish (US)
Pages (from-to)13-22
Number of pages10
JournalPediatric dermatology
Volume2
Issue number1
DOIs
StatePublished - Jul 1984

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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