Abstract: Cicatricial pemphigoid has been documented previously in only four patients under the age of 20 years. We report a 6‐year‐old male who had erosions of the oral and genital mucosa, conjunctivitis, hoarseness, dysphagia, recurrent vomiting, and weight loss. Upper airway obstruction due to a chronically inflamed and scarred epiglottis necessitated tracheostomy. Biopsy of tissue from a solitary cutaneous lesion demonstrated a subepidennal bulla. Direct and indirect immunofluorescence confirmed a diagnosis of cicatricial pemphigoid. Therapy was begun consisting of prednisone, 2 mg per kg per day, in combination with dapsone, 2 mg per kg per day. He did not improve until the prednisone dosage was increased to 4 mg per kg per day.
|Original language||English (US)|
|Number of pages||10|
|State||Published - Jul 1984|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health