Cilia in vertebrate development and disease

Edwin C. Oh, Elias Nicholas Katsanis

Research output: Contribution to journalArticlepeer-review

137 Scopus citations


Through the combined study of model organisms, cell biology, cell signaling and medical genetics we have significantly increased our understanding of the structure and functions of the vertebrate cilium. This ancient organelle has now emerged as a crucial component of certain signaling and sensory perception pathways in both developmental and homeostatic contexts. Here, we provide a snapshot of the structure, function and distribution of the vertebrate cilium and of the pathologies that are associated with its dysfunction.

Original languageEnglish (US)
Pages (from-to)443-448
Number of pages6
Issue number3
StatePublished - Feb 1 2012


  • Cilia
  • IFT
  • Signaling

ASJC Scopus subject areas

  • Molecular Biology
  • Developmental Biology


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