Circadian clocks in a wide range of organisms are thought to consist of two interdependent transcriptional feedback loops. In Drosophila, the first loop has been well characterized and controls rhythmic period expression. In this issue of Cell, Cyran et al. (2003) define a role for a transcriptional activator and a repressor in the second feedback loop.
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)