Circadian Rhythm Sleep-Wake Disorders

Phyllis C. Zee, Sabra M. Abbott*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

2 Scopus citations


PURPOSE OF REVIEW This article provides an overview of circadian physiology and discusses common presentations and treatment strategies for the circadian rhythm sleep-wake disorders. RECENT FINDINGS Circadian rhythms are present throughout the body, and appreciation for the role that circadian dysregulation plays in overall health is increasing, with mounting associations between circadian disruption and cardiometabolic disease risk. SUMMARY It is important to recognize the ubiquitous role that circadian rhythms play throughout the brain and body. An understanding of circadian neurophysiology will provide insight into the means by which patients with a variety of neuropathologies at the level of the retina, optic nerve, or hypothalamus may also be at risk for circadian dysfunction.

Original languageEnglish (US)
Pages (from-to)988-1002
Number of pages15
JournalCONTINUUM Lifelong Learning in Neurology
Issue number4
StatePublished - Aug 1 2020

ASJC Scopus subject areas

  • Clinical Neurology
  • Genetics(clinical)


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