Circadian Rhythms: Implications for Health and Disease

Sabra M. Abbott, Phyllis C. Zee*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Circadian rhythms are present in nearly all organisms studied, and are present throughout the human body. The proper coordination of these rhythms, both within the body, and with respect to the environment appears to be important for overall health. This article reviews the available data looking at the association between circadian dysregulation and cardiometabolic, neurologic, and neurodegenerative disease risk. In addition we discuss the limited but growing evidence supporting the use of circadian-based interventions to improve overall health.

Original languageEnglish (US)
Pages (from-to)601-613
Number of pages13
JournalNeurologic clinics
Issue number3
StatePublished - Aug 2019


  • Aging
  • Cardiometabolic disease
  • Circadian
  • Neurodegeneration

ASJC Scopus subject areas

  • Clinical Neurology


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