TY - JOUR
T1 - Circulating 25-hydroxyVitamin D and physical performance in older adults
T2 - A nationwide study in Taiwan
AU - Chuang, Shu Chun
AU - Chen, Hui Ling
AU - Tseng, Wei Ting
AU - Wu, I. Chien
AU - Hsu, Chih Cheng
AU - Chang, Hsing Yi
AU - Ida Chen, Yii Der
AU - Lee, Marion M.
AU - Liu, Kiang
AU - Hsiung, Chao Agnes
N1 - Publisher Copyright:
© 2016 American Society for Nutrition.
PY - 2016/11/1
Y1 - 2016/11/1
N2 - Background: A previous study indicated that 31% of the elderly in Taiwan have a Vitamin D deficiency. Vitamin D adequacy has been associated with physical performance in the elderly. Objectives: The first aim of the current study was to identify the determinants for Vitamin D deficiency. The second aim was to evaluate the association between Vitamin D status and physical performance. Design: A total of 5664 community-dwelling participants aged 55 y were recruited since 2008. Plasma total 25-hydroxyVitamin D concentrations were originally determined by ELISA and calibrated to a chemiluminescence measurement. Physical performance was assessed by handgrip strength, the Short Physical Performance Battery, timed up and go, a 6-min walk test, and single-leg stands. Multiple linear regression and logistic regression were used to estimate the cross-sectional associations. Results: Vitamin D inadequacy (,50 nmol/L) was related to higher education (P-trend , 0.01), body mass index [(BMI; in kg/m2) ORs (95% CIs) for 30 compared with 18.5 to ,25 were 1.78 (1.14, 2.78) for men and 1.53 (1.11, 2.11) for women], and vegetable intake [fourth compared with first quartile, 1.58 (1.15, 2.18) for men and 2.38 (1.82, 3.12) for women]. Higher intakes of fish [fourth compared with first quartile, 0.44 (0.33, 0.59) for men and 0.27 (0.21, 0.36) for women] and milk [fourth compared with first quartile, 0.46 (0.31, 0.69) for men and 0.69 (0.49, 0.95) for women] were associated with lower risk of Vitamin D inadequacy. Few subjects had 25-hydroxyVitamin D concentrations ,30 nmol/L. Above that concentration, there was no doseeffect relation with physical performance except for single-leg stands. Conclusions: The factors associated with Vitamin D inadequacy in Taiwan were higher education, higher BMI, and lower fish and milk intakes. No dose-effect relation existed between Vitamin D concentration and physical performance except for single-leg stands.
AB - Background: A previous study indicated that 31% of the elderly in Taiwan have a Vitamin D deficiency. Vitamin D adequacy has been associated with physical performance in the elderly. Objectives: The first aim of the current study was to identify the determinants for Vitamin D deficiency. The second aim was to evaluate the association between Vitamin D status and physical performance. Design: A total of 5664 community-dwelling participants aged 55 y were recruited since 2008. Plasma total 25-hydroxyVitamin D concentrations were originally determined by ELISA and calibrated to a chemiluminescence measurement. Physical performance was assessed by handgrip strength, the Short Physical Performance Battery, timed up and go, a 6-min walk test, and single-leg stands. Multiple linear regression and logistic regression were used to estimate the cross-sectional associations. Results: Vitamin D inadequacy (,50 nmol/L) was related to higher education (P-trend , 0.01), body mass index [(BMI; in kg/m2) ORs (95% CIs) for 30 compared with 18.5 to ,25 were 1.78 (1.14, 2.78) for men and 1.53 (1.11, 2.11) for women], and vegetable intake [fourth compared with first quartile, 1.58 (1.15, 2.18) for men and 2.38 (1.82, 3.12) for women]. Higher intakes of fish [fourth compared with first quartile, 0.44 (0.33, 0.59) for men and 0.27 (0.21, 0.36) for women] and milk [fourth compared with first quartile, 0.46 (0.31, 0.69) for men and 0.69 (0.49, 0.95) for women] were associated with lower risk of Vitamin D inadequacy. Few subjects had 25-hydroxyVitamin D concentrations ,30 nmol/L. Above that concentration, there was no doseeffect relation with physical performance except for single-leg stands. Conclusions: The factors associated with Vitamin D inadequacy in Taiwan were higher education, higher BMI, and lower fish and milk intakes. No dose-effect relation existed between Vitamin D concentration and physical performance except for single-leg stands.
KW - Epidemiology
KW - HALST
KW - Lifestyle factors
KW - Physical performance
KW - Vitamin D
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U2 - 10.3945/ajcn.115.122804
DO - 10.3945/ajcn.115.122804
M3 - Article
C2 - 27733394
AN - SCOPUS:84994335510
SN - 0002-9165
VL - 104
SP - 1334
EP - 1344
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
IS - 5
ER -