Clamp-crushing vs. radiofrequency-assisted liver resection: Changes in liver function tests

Ivan Palibrk*, Biljana Milicic, Ljuba Stojiljkovic, Nebojsa Manojlovic, Vladimir Dugalic, Vesna Bumbasirevic, Nevena Kalezic, Marinko Zuvela, Miroslav Milicevic

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Background/Aims: Liver resection is the gold standard in managing patients with metastatic or primary liver cancer. The aim of our study was to compare the traditional clamp-crushing technique to the radiofrequency-assisted liver resection technique in terms of postoperative liver function. Methodology: Liver function was evaluated preoperatively and on postoperative days 3 and 7. Liver synthetic function parameters (serum albumin level, prothrombin time and international normalized ratio), markers of hepatic injury and necrosis (serum alanine aminotransferase, aspartate aminotransferase and total bilirubin level) and microsomal activity (quantitative lidocaine test) were compared. Results: Forty three patients completed the study (14 had clamp-crushing and 29 had radiofrequency assisted liver resection). The groups did not differ in demographic characteristics, pre-operative liver function, operative time and perioperative transfusion rate. In postoperative period, there were similar changes in monitored parameters in both groups except albumin levels, that were higher in radiofrequency-assisted liver resection group (p=0.047). Conclusions: Both, traditional clamp-crushing technique and radiofrequency assisted liver resection technique, result in similar postoperative changes of most monitored liver function parameters.

Original languageEnglish (US)
Pages (from-to)800-804
Number of pages5
Issue number115
StatePublished - May 1 2012


  • Liver function parameters
  • Liver resection

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology


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