Classical and anaplastic seminoma: Difference in survival

V. S. Bobba, Bharat B Mittal, S. V. Hoover, A. Kepka

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

Classical and anaplastic seminoma are traditionally treated with radiation therapy and are said to have the same prognosis. A retrospective study was undertaken of 90 seminoma patients treated with radiation therapy between 1961 and 1985. The classical group consisted of 71 patients of whom 50 had stage I and 21 had stage II disease. The anaplastic group consisted of 19 patients of whom ten had stage I and nine had stage II disease. The median follow-up time was 64 months for the entire group. The 10-year relapse-free survival rate for the classical group was 94% and for the anaplastic group was 70% (P < .05). For patients with classical stage I disease, the relapse-free actuarial survival rate was 98%; for patients with anaplastic stage I disease, it was 64% (P < .02). For the classical stage II disease group, the relapse-free actuarial survival rate was 84% and for the anaplastic stage II disease group, 75% (P < .70). Four patients in the classical group (6%) had relapses; of these, one patient had local recurrence of tumor, and three had distant metastases. In the anaplastic group, four patients (21%) had relapses; two patients had local recurrence of tumor, and two had distant metastases. Therefore the data suggest a difference in survival and relapse rates between classical and anaplastic seminoma.

Original languageEnglish (US)
Pages (from-to)849-852
Number of pages4
JournalRadiology
Volume167
Issue number3
DOIs
StatePublished - Jan 1 1988

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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