Abstract
Post-hematopoietic stem cell transplantation (HSCT) adenovirus infections were identified in 31 of 204 consecutive pediatric HSCT patients, 18 of whom had severe manifestations of infection. Cidofovir treatment led to clinical improvement in 8 of 10 patients with severe infection and to virologic clearance in 9 patients. In vitro susceptibility to cidofovir was demonstrated in 12 clinical adenovirus isolates. Cidofovir is a promising treatment option for this population.
Original language | English (US) |
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Pages (from-to) | 1812-1816 |
Number of pages | 5 |
Journal | Clinical Infectious Diseases |
Volume | 41 |
Issue number | 12 |
DOIs | |
State | Published - Dec 15 2005 |
ASJC Scopus subject areas
- Microbiology (medical)
- Infectious Diseases