Clinical approach to antibody-mediated rejection from the pediatric heart transplant society

Shahnawaz Amdani; Heather Henderson; Melanie D. Everitt; Gary Beasley; Renata Shih; Vernat Exil; Juan Alejos; Gonzalo Wallis; Estela Azeka; Deipanjan Nandi; Elizabeth Profita; Joseph Spinner; Defne Magnetta; Hugo Martinez; Matthew Fenton; Jennifer Conway; Simon Urschel

doi:10.1111/petr.14398

Clinical approach to antibody-mediated rejection from the pediatric heart transplant society

Shahnawaz Amdani^*, Heather Henderson, Melanie D. Everitt, Gary Beasley, Renata Shih, Vernat Exil, Juan Alejos, Gonzalo Wallis, Estela Azeka, Deipanjan Nandi, Elizabeth Profita, Joseph Spinner, Defne Magnetta, Hugo Martinez, Matthew Fenton, Jennifer Conway, Simon Urschel

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: This document is designed to outline the definition, pathogenesis, diagnostic modalities and therapeutic measures to treat antibody-mediated rejection in children postheart transplant. Methods: Literature review was conducted by a Pediatric Heart Transplant Society (PHTS) working group to identify existing pediatric and adult studies on antibody-mediated rejection (AMR). In addition, the centers participating in PHTS were asked to submit their approach to diagnosis and management of pediatric AMR. This document synthesizes information gathered from both these sources to highlight a practical approach to diagnosing and managing a child with AMR postheart transplant. This document may not represent the practice at all centers in the PHTS and serves as a starting point to understand an approach to this clinical scenario.

Original language	English (US)
Article number	e14398
Journal	Pediatric transplantation
Volume	26
Issue number	8
DOIs	https://doi.org/10.1111/petr.14398
State	Published - Dec 2022
Externally published	Yes

Keywords

AMR
heart transplant
pediatric

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Transplantation

Access to Document

10.1111/petr.14398

Cite this

Amdani, S., Henderson, H., Everitt, M. D., Beasley, G., Shih, R., Exil, V., Alejos, J., Wallis, G., Azeka, E., Nandi, D., Profita, E., Spinner, J., Magnetta, D., Martinez, H., Fenton, M., Conway, J., & Urschel, S. (2022). Clinical approach to antibody-mediated rejection from the pediatric heart transplant society. Pediatric transplantation, 26(8), [e14398]. https://doi.org/10.1111/petr.14398

@article{23fc06fa281b4a39bc496620db332c98,

title = "Clinical approach to antibody-mediated rejection from the pediatric heart transplant society",

abstract = "Objective: This document is designed to outline the definition, pathogenesis, diagnostic modalities and therapeutic measures to treat antibody-mediated rejection in children postheart transplant. Methods: Literature review was conducted by a Pediatric Heart Transplant Society (PHTS) working group to identify existing pediatric and adult studies on antibody-mediated rejection (AMR). In addition, the centers participating in PHTS were asked to submit their approach to diagnosis and management of pediatric AMR. This document synthesizes information gathered from both these sources to highlight a practical approach to diagnosing and managing a child with AMR postheart transplant. This document may not represent the practice at all centers in the PHTS and serves as a starting point to understand an approach to this clinical scenario.",

keywords = "AMR, heart transplant, pediatric",

author = "Shahnawaz Amdani and Heather Henderson and Everitt, {Melanie D.} and Gary Beasley and Renata Shih and Vernat Exil and Juan Alejos and Gonzalo Wallis and Estela Azeka and Deipanjan Nandi and Elizabeth Profita and Joseph Spinner and Defne Magnetta and Hugo Martinez and Matthew Fenton and Jennifer Conway and Simon Urschel",

note = "Publisher Copyright: {\textcopyright} 2022 Wiley Periodicals LLC.",

year = "2022",

month = dec,

doi = "10.1111/petr.14398",

language = "English (US)",

volume = "26",

journal = "Pediatric Transplantation",

issn = "1397-3142",

publisher = "Wiley-Blackwell",

number = "8",

}

Amdani, S, Henderson, H, Everitt, MD, Beasley, G, Shih, R, Exil, V, Alejos, J, Wallis, G, Azeka, E, Nandi, D, Profita, E, Spinner, J, Magnetta, D, Martinez, H, Fenton, M, Conway, J & Urschel, S 2022, 'Clinical approach to antibody-mediated rejection from the pediatric heart transplant society', Pediatric transplantation, vol. 26, no. 8, e14398. https://doi.org/10.1111/petr.14398

TY - JOUR

T1 - Clinical approach to antibody-mediated rejection from the pediatric heart transplant society

AU - Amdani, Shahnawaz

AU - Henderson, Heather

AU - Everitt, Melanie D.

AU - Beasley, Gary

AU - Shih, Renata

AU - Exil, Vernat

AU - Alejos, Juan

AU - Wallis, Gonzalo

AU - Azeka, Estela

AU - Nandi, Deipanjan

AU - Profita, Elizabeth

AU - Spinner, Joseph

AU - Magnetta, Defne

AU - Martinez, Hugo

AU - Fenton, Matthew

AU - Conway, Jennifer

AU - Urschel, Simon

PY - 2022/12

Y1 - 2022/12

N2 - Objective: This document is designed to outline the definition, pathogenesis, diagnostic modalities and therapeutic measures to treat antibody-mediated rejection in children postheart transplant. Methods: Literature review was conducted by a Pediatric Heart Transplant Society (PHTS) working group to identify existing pediatric and adult studies on antibody-mediated rejection (AMR). In addition, the centers participating in PHTS were asked to submit their approach to diagnosis and management of pediatric AMR. This document synthesizes information gathered from both these sources to highlight a practical approach to diagnosing and managing a child with AMR postheart transplant. This document may not represent the practice at all centers in the PHTS and serves as a starting point to understand an approach to this clinical scenario.

AB - Objective: This document is designed to outline the definition, pathogenesis, diagnostic modalities and therapeutic measures to treat antibody-mediated rejection in children postheart transplant. Methods: Literature review was conducted by a Pediatric Heart Transplant Society (PHTS) working group to identify existing pediatric and adult studies on antibody-mediated rejection (AMR). In addition, the centers participating in PHTS were asked to submit their approach to diagnosis and management of pediatric AMR. This document synthesizes information gathered from both these sources to highlight a practical approach to diagnosing and managing a child with AMR postheart transplant. This document may not represent the practice at all centers in the PHTS and serves as a starting point to understand an approach to this clinical scenario.

KW - AMR

KW - heart transplant

KW - pediatric

UR - http://www.scopus.com/inward/record.url?scp=85141935259&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85141935259&partnerID=8YFLogxK

U2 - 10.1111/petr.14398

DO - 10.1111/petr.14398

M3 - Article

C2 - 36377325

AN - SCOPUS:85141935259

SN - 1397-3142

VL - 26

JO - Pediatric Transplantation

JF - Pediatric Transplantation

IS - 8

M1 - e14398

ER -

Clinical approach to antibody-mediated rejection from the pediatric heart transplant society

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this