Abstract
Surgical resection or liver transplantation offers the best chance of cure for patients with hepatocellular carcinoma (HCC). Unfortunately, most patients are not good candidates for liver resection due to locally advanced disease or compromised liver function. Moreover, liver transplantation waiting lists are long. For those cases not amenable for resection, a variety of local treatment modalities are available, such as image-guided ablative procedures, transarterial chemoembolization, and radioembolization, as well as external beam radiation. HCC presentation can vary considerably in size, number, and location of lesions. The management of inoperable HCC is, therefore, quite complex, and there is a lack of consensus on the best local treatment modality for each type tumor presentation. Here, we present 4 clinical case scenarios representative of commonly seen cases in the clinical setting, with different therapeutic perspectives from institutions with high expertise in the management of HCC.
Original language | English (US) |
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Pages (from-to) | 295-308 |
Number of pages | 14 |
Journal | Seminars in Radiation Oncology |
Volume | 28 |
Issue number | 4 |
DOIs | |
State | Published - Oct 2018 |
Funding
Daniel T. Chang, MD has stock on ViewRay, Inc and received honoraria and research funding from Varian Medical Systems, Inc. For the remaining authors, none were declared.
ASJC Scopus subject areas
- Oncology
- Radiology Nuclear Medicine and imaging
- Cancer Research