Clinical case report: Chronic pruritus and cholestasis

O. L. De Mola*, C. Burnweit, P. F. Whitington

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Recent advances in the differential diagnosis of chronic cholestasis in the pediatric age group have made us aware of a heterogeneous group of children who have progressive familial intrahepatic cholestasis (PFIC). This particular case illustrates the importance of early recognition and treatment, which is surgical (partial biliary diversion) since - with proper surgical intervention before the onset of cirrhosis, or bridging fibrosis - the pruritus disappears and the progression to end-stage liver disease is halted. This case elucidates some of the typical historical, clinical, and pathological characteristics of progressive familial intrahepatic cholestasis.

Original languageEnglish (US)
Pages (from-to)233-235
Number of pages3
JournalInternational Pediatrics
Issue number3
StatePublished - Jan 1 1995

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


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