Clinical factors that may confound the assessment of drug efficacy

J. G. Csernansky, J. W. Newcomer, L. S. Miller, W. O. Faustman

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

The development of new chemical classes of psychotherapeutic drugs offers the potential for new patterns of drug efficacy as well as decreases in side effects. However, the determination of drug efficacy can be confounded by sample selection and outcome determination factors. The ability of selected clinical factors of both types to affect the outcome of antipsychotic drug trials is reviewed. Suggestions for future clinical drug trials are made.

Original languageEnglish (US)
Pages (from-to)231-235
Number of pages5
JournalPsychopharmacology Bulletin
Volume27
Issue number3
StatePublished - Jan 1 1991

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Pharmacology

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  • Cite this

    Csernansky, J. G., Newcomer, J. W., Miller, L. S., & Faustman, W. O. (1991). Clinical factors that may confound the assessment of drug efficacy. Psychopharmacology Bulletin, 27(3), 231-235.