Clinical, genetic, and biophysical characterization of SCN5A mutations associated with atrioventricular conduction block

Keyphrases

• Biophysical Characterization 100%
• SCN5A mutation 100%
• Clinical Characterization 100%
• SCN5A 100%
• Clinical Genetics 100%
• Genetic Characterization 100%
• Atrioventricular Conduction Disturbance 100%
• Atrioventricular Block 66%
• Functional Consequences 33%
• Channel Subunits 33%
• Ventricular Arrhythmia 33%
• Action Potential 33%
• Clinical Phenotype 33%
• Voltage-gated Sodium Channel 33%
• Long QT Syndrome 33%
• Patch-clamp Recording 33%
• Biophysical Characteristics 33%
• Redundant mutants 33%
• Clinical Features 33%
• Conduction System Disease 33%
• Fast Inactivation 33%
• Sodium Current 33%
• Glycine 33%
• Distinct Patterns 33%
• Genetic Features 33%
• Heterozygous mutation 33%
• Current Density 33%
• Cultured Cell Lines 33%
• Aspartic Acid 33%
• Slow Inactivation 33%
• Asparagine 33%
• Conduction Velocity 33%
• Brugada Syndrome 33%
• Molecular Genetic Testing 33%
• Potential Simulation 33%
• Single Ion Channels 33%
• Transition mutation 33%
• S3 Segment 33%

Biochemistry, Genetics and Molecular Biology

• Genetics 100%
• Atrioventricular Conduction 100%
• Atrioventricular Block 100%
• Nerve Block 100%
• Candidate Gene 50%
• Molecular Genetics 50%
• Asparagine 50%
• Action Potential 50%
• Electric Potential 50%
• Cell Culture 50%
• Sodium Current 50%
• Heart Conduction 50%
• Current Density 50%
• Whole Cell Patch Clamp 50%
• Cardiac Dysrhythmia 50%
• Sodium Channel 50%
• Patch Clamp Technique 50%
• Brugada Syndrome 50%
• Ion Channel 50%
• Serine 50%
• Long QT Syndrome 50%
• Aspartic Acid 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Atrioventricular Block 100%
• Heart Arrhythmia 50%
• Voltage Gated Sodium Channel 50%
• Ion Channel 50%
• Aspartic Acid 50%
• Long QT Syndrome 50%
• Serine 50%
• Asparagine 50%
• Brugada Syndrome 50%
• Diseases 50%