Clinical manifestations of acromegaly

M. E. Molitch*

*Corresponding author for this work

Research output: Contribution to journalReview article

163 Scopus citations


Pituitary tumors in patients with acromegaly are usually large and may cause problems because of tumor mass and hormone oversecretion. Mortality is increased two- to threefold owing to cardiovascular, respiratory, and neoplastic causes. Early treatment may reverse the diabetes, soft tissue changes, sleep apnea, and cardiovascular and neuromuscular disease. The effect of treatment on neoplasia is unclear, and patients need screening, especially for colon neoplasia.

Original languageEnglish (US)
Pages (from-to)597-614
Number of pages18
JournalEndocrinology and Metabolism Clinics of North America
Issue number3
StatePublished - 1992

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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